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IBC Application Forms

This page is to provide you with forms and instructions for exempting or registering rDNA experiments. Note: Always check the "What's New" button on the left for announcements about new versions of forms.

Short Version

First, see “Information for IBC Registration Forms,” to understand definitions.

Single step registration – if you know you have to register your non-exempt experiment:

  • UCHC PIs use this form (Word doc) if your transgenic/gene-targeted mouse is constructed in the UCHC GTTF.
  • UCHC PIs use this form (Word doc) if your UCHC-built transgenic/gene targeted animal is built in your lab and not the GTTF.
  • Non-UCHC PIs use this form if your transgenic/gene-targeted mouse is constructed in the UCHC GTTF.
  • Form for other experiments (Word doc).
  • Form for broadscope registrations (experiments using same components repetitively).

Two step registration – if you believe your experiment may be exempt:

  • First, fill out IBC Form A (Word doc), in which you supply the host-vector-SOI systems involved.
  • Send IBC Form A to the BSO for a determination that your experiment is exempt or not.
  • If your experiment is exempt, that’s all. If not, fill out IBC Form B (Word doc). Forms A and B will be reviewed by the IBC.

Long Version

First, see Information for IBC Registration Forms,” to understand definitions.

  • If you are involved in the construction of a transgenic, knock-out or knock-in (gene-targeted) rodent at the UConn Health Center, it is not exempt and must be registered with the IBC. Just do a one step registration process and use the appropriate IBC Form in the above section.
     
  •  If you have already determined that your experiment needs to be registered, by speaking with the IBC coordinator/BSO or by other means, do a one-step registration process. Use the IBC Generic Form (Word doc). You may find accessories (Word doc) helpful for diagrams, tables and other useful stuff. If you do many repetitive experiments using the same components and procedures, you may be eligible to submit a broadscope registration using the IBC Broadscope Form.
     
  • If you want to know if your experiment is exempt to the NIH rDNA Guidelines, begin the two-step registration process. Fill out IBC Form A (Word doc) and email it to the BSO. The BSO will determine if your experiment is exempt or not or ask for clarifications until the determination* can be made.
    • If the determination is your experiment is exempt to the NIH rDNA Guidelines, you’re done for this experiment. The IBCformA will become the documentation that your experiment is exempt.
    • If the determination is your experiment is not exempt, fill out IBC Form B (Word doc) and email it to the BSO. If the BSO thinks the IBC will approve the application, consisting of IBC Form A and IBC Form B, then it will be submitted to the IBC. The BSO may ask for clarifications on your application before it will be submitted to the IBC.
    • The IBC may ask for clarifications or more information before approving a registration.
       
  • Find out how the IBC works.

* The determinations of the BSO are subject to the scrutiny and approval of the IBC. The IBC reserves the right to reverse any declarations of exemption or any biosafety level that the BSO may set. The BSO makes no claim to infallibility and reserves the right to turn to the NIH OBA or the UConn Health Center IBC for clarifications or judgments as needed. This may slow things up a bit.

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