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Human or Non-human Primate Blood, Tissues or Cell Cultures

For clinical/research work with human or non-human primate

  • blood,
  • body fluids,
  • tissues, or
  • cell cultures - primary/established (even partially tested) lines,
  • animals injected with human primary cells or cell lines,

OSHA (under the Bloodborne Pathogen [BBP] Law) and/or UConn Health Center safety policy require:

  • documented initial and then annual training,
  • documented HBV vaccination and/or adequate HBV antibody titer testing, or signing a declination,
  • observing Universal Precautions;  or in the lab, BSL-2; or while working with animals, ABSL-2.
  • following safe needle/syringe practices (see items 17 & 25),
  • following waste requirements (see items 17 & 25),
  • following labeling/signage requirements (see Section 5 of Attachment 3 of the UCHC BBP Exposure Control Plan),
  • use of a biological safety cabinet that has been certified within the last year per BSL-2 requirements (see above - when aerosols may be generated).

To answer most questions about human materials, review the annual training read the UConn Health Center Bloodborne Pathogen Control Plan, call the Office of Research Safety at 860-679-2723 and/or contact the Biological Safety Officer. Note that the BBP Law does not cover non-human primate (NHP) materials, but it is strongly recommended that for your protection, you follow Universal Precautions and/or use BSL-2 containment and practices.

Also, you may view the OSHA law and/or the OSHA interpretation of the law regarding cultures of human primary cells and cell lines.

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